Recent Publications

 

Divergent acyl carrier protein decouples mitochondrial Fe-S cluster biogenesis from fatty acid synthesis in malaria parasites

Seyi Falekun, Jaime Sepulveda, Yasaman Jami-Alahmadi, Hahnbeom Park, James A Wohlschlegel, Paul A Sigala

Elife 2021 Oct 6

Critical Role for Isoprenoids in Apicoplast Biogenesis by Malaria Parasites

Megan Okada, Krithika Rajaram, Russell P. Swift, Amanda Mixon, John Alan Maschek, Sean T. Prigge, and Paul A. Sigala

bioRxiv 2021

Doxycycline has distinct apicoplast-specific mechanisms of antimalarial activity

Megan Okada, Ping Guo, Shai-anne Nalder, Paul A Sigala the difference.

eLife 2020 Nov 2

Plasmodium heme biosynthesis: To be or not to be essential?

Goldberg DE and Sigala PA

PLoS Pathogens 13(9): e1006511 2017